Breakthrough Alzheimer's Drug Targets Key 'Hotspots' to
WEB1 day ago · Tau proteins (in red) building up in the neuronal circuits of a fruit fly. (University of Southampton) Tau proteins in the brain aren't all bad. When healthy, they help maintain the stability of a neuron's various branches. But in some Alzheimer's brains – whether as a cause or a consequence of the disease – their fibrils go into overdrive.
Brain network study reveals clues about dementia's behavior …
WEB3 hours ago · Tau protein buildup in brain disrupts the salience network that connects multiple brain regions and helps us react to the outside world and our own thoughts. Dementia doesn't just erode memory ...
New therapy that targets and destroys tau tangles is a promising …
WEBSep 16, 2024 · Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.
Dual-Targeting Drug Halts Tau Accumulation in Alzheimer’s
WEB5 days ago · Scientists have developed a drug that targets both major aggregation-promoting sites of the Tau protein, a key player in Alzheimer's disease.
Promising Alzheimer's drug candidate prevents buildup of tau …
WEB5 days ago · The drug, a peptide inhibitor called RI-AG03, was effective at preventing the buildup of tau proteins in both lab and fruit fly studies. The research, published in Alzheimer's & Dementia, was led...
New Alzheimer's Treatment Shows Promise by Dual-Targeting Tau …
WEB4 days ago · Before joining Technology Networks she researched maternal health and the microbiome. A new drug, RI-AG03, developed by researchers at the University of Southampton, targets two critical regions of the tau protein linked to Alzheimer's disease. Early tests demonstrated the drug's effectiveness in reducing tau aggregation.
A Blood Test Accurately Diagnosed Alzheimer’s 90% of the Time, …
WEBJul 28, 2024 · The new study used a blood test that focuses on a form of a protein called tau that sprouts into tangles in the brains of people with Alzheimer’s.
How Tau tangles form in the brain - MIT News
WEBJul 14, 2023 · Many neurodegenerative diseases, including Alzheimer’s, are characterized by tangled proteins called Tau fibrils. In a new study, MIT chemists have gained insight into how these fibrils form, and identified a potential target for …
Researchers find the roots of tau tangles in Alzheimer’s disease
WEBNov 3, 2023 · An experimental drug can reduce the toxic changes in tau proteins known to damage neurons in brains with Alzheimer’s disease, researchers from Yale School of Medicine and Johns Hopkins University report.
Tau-targeting therapies for Alzheimer disease: current status and ...
WEBOct 24, 2023 · This Review provides an update on the initial trials of tau-targeting therapies, focusing particularly on immunotherapies, and considers future directions for these therapies.