The brain has a waste-disposal system that clears away junk proteins that contribute to the development of dementia an ...

Dementia doesn't just erode memory -- it also changes behavior and mental health. A study shows the brain's salience network and tau protein may be involved.

A peptide inhibitor called RI-AG03 targets major aggregation “hot spots” of tau proteins, believed to be a key driver of ...

Characterised by the abnormal accumulation of two proteins, amyloid beta and phosphorylated tau (pTau), AD progresses ...

The drug is RI-AG03, and it's a peptide inhibitor (a blocker of proteins). In tests on fruit flies and human cells, it has ...

Bafana Bafana vice-captain Percy Tau has asked national team Hugo Broos to be excluded from the squad to play against Congo ...

Orlando Pirates confirmed massive news on Monday. The 2024 CAF Champions League draw was announced from Cairo, Egypt.

Innovative treatments using TRIM21 have successfully targeted tau aggregates in Alzheimer’s, showing potential for broader ...

AG03, developed by researchers at the University of Southampton, targets two critical regions of the tau protein linked to ...

DEPTAC. Based on PROTACs, or protein-targeting chimeras, D20, a dephosphorylation-targeting chimera, delivers PP1 to tau. The C-terminal tail (gray) helps the construct enter cells. [Courtesy of Xiao ...

Further research could also help explain and even predict variation in the onset of behavioral changes in people with ...

A mailed knowledge mobilization and behavior change intervention can reduce the use of sedatives and improve sleep outcomes in older adults with insomnia.