Dementia doesn't just erode memory -- it also changes behavior and mental health. A study shows the brain's salience network and tau protein may be involved.
Scientists have announced a significant breakthrough in the development of a drug to combat Alzheimer's disease. The drug, ...
An international team of researchers led by Lancaster University has made a promising breakthrough in the development of ...
The drug is RI-AG03, and it's a peptide inhibitor (a blocker of proteins). In tests on fruit flies and human cells, it has ...
An international team of researchers has made a significant breakthrough in Alzheimer's drug development with the ...
In a world-first, researchers have developed a drug that targets both critical regions of the tau protein, a key factor in Alzheimer's disease. The study, published in Alzheimer's & Dementia, has ...
DEPTAC. Based on PROTACs, or protein-targeting chimeras, D20, a dephosphorylation-targeting chimera, delivers PP1 to tau. The C-terminal tail (gray) helps the construct enter cells. [Courtesy of Xiao ...
AG03, targets two key areas of the Tau protein in Alzheimer's disease, showing effectiveness in lab and fruit fly models.
Further research could also help explain and even predict variation in the onset of behavioral changes in people with ...
Researchers from the University of Michigan reveal new insights into early-stage dementia, identifying tau protein as a ...