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Adverse drug reactions cause significant morbidity and mortality and incur a large cost to healthcare systems. Pharmacogenomics may help in the prediction and prevention of adverse reactions to drugs.
Table 1. Examples of pharmacogenomic information in drug labels. Drug name ADR Genotype(s) test Label recommendation Ref. Adverse drug reactions (ADRs) are reported to be the fourth leading cause ...
Adverse drug reactions, multimorbidity and polypharmacy: a prospective analysis of 1 month of medical admissions. BMJ Open, 2022; 12 (7): e055551 DOI: 10.1136/bmjopen-2021-055551 ...
Between January 1, 2003, and August 7, 2023, a total of 119,123 adverse drug reactions were reported in EudraVigilance. The greatest proportions of adverse drug reactions related to C difficile ...
Concerned over the widely used life-saving beta blocker drugs causing adverse drug reactions, the government’s Indian Pharmacopoeia Commission (IPC) has issued an alert about the same.
For example, it estimated a 94.06% probability of hepatotoxicity for erythromycin, 88.44% for nephrotoxicity and 75.8% for hypertension in cisplatin.
The FDA Adverse Event Reporting System, which Commissioner Marty Makary called “clunky,” previously published updates on a ...
The FDA said it has begun publishing reports of adverse events concerning drugs on a daily basis, instead of quarterly, as it ...
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