By recreating a fetal liver niche, FLOs show how liver and immune cells co-develop. Learn more about new groundbreaking ...
Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have ...
As rates of obesity, high blood pressure, type 2 diabetes and sleep apnea increase, cases of advanced chronic liver disease ...
Massachusetts Institute of Technology (MIT), engineers developed a new liver tissue model to help reveal the stages of liver regeneration in hopes to help those individuals with liver disease, ...
3D bio-printed liver model and high-content imaging for evaluating the toxicity effects of compounds
The effectiveness of non-clinical drug safety predictions is enhanced by the adoption of three-dimensional (3D) cellular models. 3D bioprinting enables the generation of complex models with spatial ...
Using human induced pluripotent stem cells, researchers have built a miniature 3D liver model that replicates the critical interaction between hepatocytes and stellate cells. As chronic liver disease ...
Absorption, Distribution, Metabolism, and Excretion (ADME) are important parameters to determine the pharmacokinetic profile of a drug, and therefore a crucial measurement for drug efficacy. Animal ...
Scientists from Uppsala University and several other research institutions have created a personalized human liver model that can significantly improve the diagnosis and treatment of diseases such as ...
Scientists from Children’s Medical Research Institute (CMRI) have successfully tested adeno-associated viral vector-based (AAV) gene therapies in whole human livers in the lab. The study, which is ...
After the recent implementation of acuity circle (AC)-based allocation policies, overall mortality and dropout rates among severely ill liver transplant candidates decreased; however, candidates with ...
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