Kyler Murray had a long touchdown run in the first quarter and rallied Arizona with two fourth-quarter scoring drives in the Cardinals' 24-23 victory over the San Francisco 49ers on Sunday. Murray threw a 2-yard touchdown pass to Elijah Higgins early in the fourth quarter that cut the deficit to 23-21 and then set up Chad Ryland's 35-yard field goal with 1:37 to play to give the Cardinals (2-3) the lead.

Kyler Murray knew it. Six yards into his 50-yard touchdown run less than two minutes into the first quarter, Arizona Cardinals quarterback knew he was gone. On first-and-10 from the 50, he faked a handoff to running back James Conner and then took off to his right.

In the first three games of the season, Arizona Cardinals quarterback Kyler Murray had five runs each week for 57, 59 and 45 yards. That production disappeared in last week’s game against the Washington Commanders when he had only one attempt