Gavin Sheets hit two of San Diego's four home runs and drove in four runs, and Fernando Tatis Jr. robbed San Francisco's Rafael Devers of a homer as the Padres beat the Giants 8-1 on Wednesday night.

Heliot Ramos, Rafael Devers and Wilmer Flores homered off Nestor Cortes in the first inning and the San Francisco Giants beat San Diego 4-3 to hand the Padres their fourth straight loss

These two weeks in which the Padres are playing only the Giants and Dodgers have provided some mood swings. The Padres moved into first place in the National League West with a sweep in San Francisco last week and fell back into second place when they were swept in Los Angeles over the weekend.

BOTTOM LINE: The San Diego Padres face the San Francisco Giants on Wednesday. San Diego has a 70-56 record overall and a 39-21 record at home. Padres hitters are batting a collective .251, which ranks fourth in the NL.

Catch the San Francisco Giants take on the San Diego Padres today Wednesday, August 20. Here's everything you need to know on how to stream the game.

San Francisco Giants starting pitcher Landen Roupp was knocked out of Wednesday night's game at the San Diego Padres in the bottom of the third inning after getting struck in the back of the right thigh by a line drive.

Giants pitcher Landen Roupp sustained a scary injury in San Francisco's game against the San Diego Padres on Wednesday at Petco Park.