Dementia doesn't just erode memory -- it also changes behavior and mental health. A study shows the brain's salience network and tau protein may be involved.
The drug is RI-AG03, and it's a peptide inhibitor (a blocker of proteins). In tests on fruit flies and human cells, it has ...
An international team of researchers led by Lancaster University has made a promising breakthrough in the development of ...
DEPTAC. Based on PROTACs, or protein-targeting chimeras, D20, a dephosphorylation-targeting chimera, delivers PP1 to tau. The C-terminal tail (gray) helps the construct enter cells. [Courtesy of Xiao ...
An international team of researchers has made a significant breakthrough in Alzheimer's drug development with the ...
Further research could also help explain and even predict variation in the onset of behavioral changes in people with ...
AG03, targets two key areas of the Tau protein in Alzheimer's disease, showing effectiveness in lab and fruit fly models.
In a world-first, researchers have developed a drug that targets both critical regions of the tau protein, a key factor in Alzheimer's disease. The study, published in Alzheimer's & Dementia, has ...
GT-02287 Demonstrates Disease Modifying Capacity in Both GBA1 and Idiopathic Parkinson’s Disease ModelsGT-02287 Improves Mitochondrial Function ...
Researchers from the University of Michigan reveal new insights into early-stage dementia, identifying tau protein as a ...