The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

The 49ers (2-3) blew a 10-point, fourth-quarter lead and fell 24-23 to the visiting Arizona Cardinals in record heat at ...

The Cardinals bounced back from a blowout loss to the Commanders to rally for a comeback win against the 49ers.

Two weeks after blowing a 24-14 lead in the fourth quarter to the Los Angeles Rams, the Niners (2-3) did it again Sunday.

The 49ers just blew another 10-point fourth quarter lead and lost 24-23 to the Arizona Cardinals. Now the 49ers are 2-3. Here ...

San Francisco 49ers running back Christian McCaffrey won't return in Week 6, but will likely make his long-awaited comeback ...

It was a good day for the future of the Las Vegas Raiders. Not because of what happened in their matchup against the Denver ...

Kyler Murray had a long touchdown run in the first quarter and rallied Arizona with two fourth-quarter scoring drives in the ...

The San Francisco 49ers (2-2) meet a fellow NFC West foe when they host the Arizona Cardinals (1-3) on Sunday, October 6, ...

Arizona shuts down San Francisco in second half to stage late rally after trailing by as much as 13 points on the road.

The record-breaking heat at Levi's Stadium on Sunday sent San Francisco 49ers fans to the concourses to watch the game on ...