Science Daily9h
Brain network study reveals clues about dementia's behavior changes
Dementia doesn't just erode memory -- it also changes behavior and mental health. A study shows the brain's salience network and tau protein may be involved.
Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies
An international team of researchers led by Lancaster University has made a promising breakthrough in the development of ...
McKnight's Long-Term Care News1d
Promising new Alzheimer’s drug candidate developed by international research team
A peptide inhibitor called RI-AG03 targets major aggregation “hot spots” of tau proteins, believed to be a key driver of ...
‘One-of-a-kind’ new Alzheimer’s drug shows promise: ‘An exciting development’
“This research is taking promising steps towards a new one-of-a-kind therapy which targets tau, a damaging protein in the ...
EuropaWire4d
Breakthrough Peptide Inhibitor Targets Tau Protein Aggregation, Paving the Way for New Alzheimer’s Treatments
An international team of researchers has made a significant breakthrough in Alzheimer's drug development with the ...
technologynetworks5d
New Alzheimer's Treatment Shows Promise by Dual-Targeting Tau Protein
In a world-first, researchers have developed a drug that targets both critical regions of the tau protein, a key factor in Alzheimer's disease. The study, published in Alzheimer's & Dementia, has ...
Alzheimer’s Game Changer: Dual-Action Drug Attacks Disease at Its Core
AG03, targets two key areas of the Tau protein in Alzheimer's disease, showing effectiveness in lab and fruit fly models.
ALZFORUM2d
Chimeric Protein Dephosphorylates Tau, Improves Memory
DEPTAC. Based on PROTACs, or protein-targeting chimeras, D20, a dephosphorylation-targeting chimera, delivers PP1 to tau. The C-terminal tail (gray) helps the construct enter cells. [Courtesy of Xiao ...
News Medical on MSN1d
Understanding behavioral changes in early dementia
Further research could also help explain and even predict variation in the onset of behavioral changes in people with ...
devdiscourse1d
New Insights into Dementia: Tau Protein's Role in Behavioral Changes
Researchers from the University of Michigan reveal new insights into early-stage dementia, identifying tau protein as a ...