Dementia doesn't just erode memory -- it also changes behavior and mental health. A study shows the brain's salience network and tau protein may be involved.
An international team of researchers led by Lancaster University has made a promising breakthrough in the development of ...
The drug is RI-AG03, and it's a peptide inhibitor (a blocker of proteins). In tests on fruit flies and human cells, it has ...
In a world-first, researchers have developed a drug that targets both critical regions of the tau protein, a key factor in Alzheimer's disease. The study, published in Alzheimer's & Dementia, has ...
AG03, targets two key areas of the Tau protein in Alzheimer's disease, showing effectiveness in lab and fruit fly models.
An international team of researchers has made a significant breakthrough in Alzheimer's drug development with the ...
DEPTAC. Based on PROTACs, or protein-targeting chimeras, D20, a dephosphorylation-targeting chimera, delivers PP1 to tau. The C-terminal tail (gray) helps the construct enter cells. [Courtesy of Xiao ...
Further research could also help explain and even predict variation in the onset of behavioral changes in people with ...
GT-02287 Demonstrates Disease Modifying Capacity in Both GBA1 and Idiopathic Parkinson’s Disease ModelsGT-02287 Improves Mitochondrial Function ...
Researchers from the University of Michigan reveal new insights into early-stage dementia, identifying tau protein as a ...